Ovis XENODouble-coated Ca-P crystal + Calf bone

Bovine bone grafting material of natural cancellous bone

  • Australian calf bone strictly managed from farming, slaughtering to transport
  • The double-coated Ca-P is highly reactive with cells and is fully combined with osteoclasts and osteoblasts, in order to continuously promote new bone formation and growth
  • Ovis XENO
  • Ovis XENO
  • Ovis XENO
  • Ovis XENO

Microstructure

Double-coated Ca-P crystal

Animal testing on mice (After 12 weeks)

  • A new bone was formed around the bone grafting material in the margin of the defect.
    The direct contact between the new bone and the bone grafting material was clearly observed.
  • OB : Old Bone, NB : New Bone, O : Ovis XENO

Bone remodeling process

  • Ovis XENO double-coated with Ca-p
  • Coatead Ca-p having electronic charge srimulates growth factors(PDGF,TGF-β,IGF)

  • Growth factors differentiate and
    proliferate mesenchymal cells
    into osteoblasts

    Osteoclast becomes active to absorb the grafted bone

    Effect of Outer layer

  • Combining with osteoblast consistently stimulates
    new bone formation

    Effect of Inner layer

  • Transplanted Ovis XENO
    then switched to
    autogenous bone

Features

  • Natural mineral bone obtained through strict manufacturing process
  • No immunologic rejection
  • Biocompatibility and great bioactivity
  • Easy revascularization of the bone graft site
  • Well-formed Macro/Micro porous similar to human’s cancellous bone

Indication for use

Hydrate Ovis XENO in a vial with blood from the defect or with saline. Deliver Ovis XENO in situ.

  • Periodontal bone defect
  • Extraction site
  • Sinus Lift
  • Intrabony defect
  • Ridge augmentation
  • Cystic cavities
Type Size(mm) Weight(g)
Vial type 0.25 - 1.0 0.15 / 0.25 / 0.5 / 1.0
1.0 - 2.0